Low blood serum levels can increase the risk of what wound-related issue?

Low blood serum levels, particularly of proteins such as albumin, can significantly impact wound healing and skin integrity by increasing the risk of pressure injuries. When serum levels are low, it often indicates poor nutrition or malnutrition, which are critical factors in maintaining skin health and resilience. Insufficient protein levels can lead to a weakened dermal structure, making the skin more susceptible to pressure and shear forces. This can result in the breakdown of skin integrity, ultimately leading to pressure injuries, especially in at-risk populations like those with limited mobility.

In addition, lower serum levels can also impair the overall healing process as proteins play a vital role in various biological functions, including tissue repair and regeneration. While other factors like infection, inflammation, and altered coagulation can be influenced by serum levels, the primary concern related to low serum protein levels and their direct link to tissue health and susceptibility to damage strongly supports the association with an increased risk of pressure injuries.